This is my profile for the F/A-18. I use VR and so with this I don't need to use a mouse. In the VR options menu disable the mouse.
All the buttons on the throttle are modifiers. See the picture to see what is bound. One speciality is that the TDC uses the main joystick with X and B3 modifiers held, so it takes a bit of getting used to, but works quicker than the POV.
Ejection Seat is not shown on the picture, Hold B3 and B4, then press B5 three times.